The world’s first in-vivo tear osmolarity testing device
  • Quantitative measurement – easy to record and follow over time
  • Rapid results – less than 5 seconds
  • Handheld, light & simple to use
  • Affordable point-of-care testing
The I-PEN® is for professional in-vivo diagnostic use only.
I-PEN®, the world’s first, hand-held in-vivo device that measures tear film osmolarity levels associated with marginal, mild, moderate and severe DED. The I-PEN®, an in practice dry eye screening device, provides rapid and reliable tear osmolarity levels patient presenting with dry eye symptoms as well as pre- and post-surgical cases. The tear osmolarity number, is an invaluable tool to monitor and to easily communicate to a patient’s the state and progression of their DED. I-PEN® results are reproducible, accurate and reliable. The I-PEN® requires:
  • Single-Use-Sensors (SUS) sold separately (link to SUS page)
  • Replacement battery CR2032 (available at most retailers)
See how to use I-PEN® Tear Osmolarity Device
How does it work?
  • The I-PEN® Tear Osmolarity System is a handheld device that measures the osmolarity (concentration of dissolved salts in solution) of human tears in normal and dry eye disease (DED) patients.
  • The I-PEN® Tear Osmolarity system, used with the I-PEN® Single-Use- Sensors (SUS), provides a quick and simple method for determining tear osmolarity by measuring the tear soaked palpebral conjunctiva. After approximately 2 seconds of contact with the eyelid tissue, the I-PEN® displays a numerical tear osmolarity test result on the liquid crystal display (LCD) in units of mOsms/L with no calculations required. The I-PEN® measures the electrical impedance in the tear soaked tissues 192 times in approximately 2 seconds and calculates the corresponding osmolarity of the tear film of the eye.

Click here for the I-PEN® manual for visual directions

For more information about the I-PEN® or to arrange for an in-office demonstration, please contact your local I-MED Pharma Sales Representative.


I-PEN® Single-Use-Sensor
Disposable sensors designed for the safety of your patients

Single-Use-Sensors (SUS) are designed for in-vivo use with the I-PEN® Tear Osmolarity System.
  • Accurate and Reliable
  • Individually Wrapped
  • Single Use
  • Affordable
One SUS per eye Box of 50 sensors



I-PEN® Osmolarity Tracker Cards

Patients can leave your office with a tangible measurement of osmolarity

(50 free cards with every I-PEN purchase)


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